MSc in Bioinformatics in Germany

What Is Bioinformatics?

Bioinformatics  is the application of statistics and computer science to the field of molecular biology.

The primary goal of bioinformatics is to increase the understanding of biological processes. What sets it apart from other approaches, however, is its focus on developing and applying computationally intensive techniques (e.g., pattern recognition, data mining, machine learning algorithms, and visualization) to achieve this goal.
The term bioinformatics was coined by Paulien Hogeweg and Ben Hesper in 1978 for the study of informatic processes in biotic systems. Its primary use since at least the late 1980s has been in genomics and genetics, particularly in those areas of genomics involving large-scale DNA sequencing.

Bioinformatics now entails the creation and advancement of databases, algorithms, computational and statistical techniques and theory to solve formal and practical problems arising from the management and analysis of biological data.

Why Is Bioinformatics So Important?

Although a human disease may not be found in exactly the same form in animals, there may be sufficient data for an animal model that allow researchers to make inferences about the process in humans.

The rationale for applying computational approaches to facilitate the understanding of various biological processes includes:

• a more global perspective in experimental design
• the ability to capitalize on the emerging technology of database-mining - the process by which testable hypotheses are generated regarding the function or structure of a gene or protein of interest by identifying similar sequences in better characterized organisms

Universities' Mission

• To provide freely available data and bioinformatics services to all facets of the scientific community in ways that promote scientific progress
• To contribute to the advancement of biology through basic investigator-driven research in bioinformatics
• To provide advanced bioinformatics training to scientists at all levels, from PhD students to independent investigators
• To help disseminate cutting-edge technologies to industry

Career Oppurtunities

Over the past few decades rapid developments in genomic and other molecular research technologies and developments in information technologies have combined to produce a tremendous amount of information related to molecular biology. It is the name given to these mathematical and computing approaches used to glean understanding of biological processes.
Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning different DNA and protein sequences to compare them and creating and viewing 3-D models of protein structures.

The rapidly emerging field of bioinformatics promises to lead to advances in understanding basic biological processes and, in turn, advances in the diagnosis, treatment, and prevention of many genetic diseases. Bioinformatics has transformed the discipline of biology from a purely lab-based science to an information science as well. Increasingly, biological studies begin with a scientist conducting vast numbers of database and Web site searches to formulate specific hypotheses or to design large-scale experiments. The implications behind this change, for both science and medicine, are staggering.

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